Research Library

Association of Legionella pneumophila with the macrophage endoplasmic reticulum

Michele S. Swanson, Ralph R. Isberg

Infection and Immunity

Legionella pneumophila replicates within a membrane-bounded compartment that is studded with ribosomes. In this study we investigated whether these ribosomes originate from the cytoplasmic pool or...

Effects of Alcohols on Micro-Organisms

L. O. Ingram, Thomas M. Buttke

Advances in microbial physiology/Advances in Microbial Physiology

Same species, different diseases: how and why typhoidal and non-typhoidal Salmonella enterica serovars differ

Ohad Gal‐Mor, Erin C. Boyle, Guntram A. Graßl

Frontiers in Microbiology

Human infections by the bacterial pathogen Salmonella enterica represent major disease burdens worldwide. This highly ubiquitous species consists of more than 2600 different serovars that can be...

Oral rivaroxaban versus standard therapy for the treatment of symptomatic venous thromboembolism: a pooled analysis of the EINSTEIN-DVT and PE randomized studies

Martin H. Prins, Anthonie WA Lensing, Rupert Bauersachs +10

Thrombosis Journal

ClinicalTrials.gov, NCT00439777; EINSTEIN-DVT: ClinicalTrials.gov, NCT00440193.

Mucin-bacterial interactions in the human oral cavity and digestive tract

Muriel Derrien, Mark W.J. van Passel, Jeroen H.B. van de Bovenkamp +3

Gut Microbes

Mucins are a family of heavily glycosylated proteins that are the major organic components of the mucus layer, the protective layer covering the epithelial cells in many human and animal organs,...

Zip14 (Slc39a14) mediates non-transferrin-bound iron uptake into cells

Juan P. Liuzzi, Fikret Aydemir, Hyeyoung Nam +2

Proceedings of the National Academy of Sciences

Zip14 is a member of the SLC39A zinc transporter family, which is involved in zinc uptake by cells. Up-regulation of Zip14 by IL-6 appears to contribute to the hepatic zinc accumulation and...

Differential modulation of Toll-like receptors by fatty acids: preferential inhibition by n-3 polyunsaturated fatty acids

Joo Young Lee, Anthony Plakidas, Won Hee Lee +4

Journal of Lipid Research

Human subjects consuming fish oil showed a significant suppression of cyclooxygenase-2 (COX-2) expression in blood monocytes when stimulated in vitro with lipopolysaccharide (LPS), an agonist for...

Bacteriocins and their Food Applications

H. Chen And, Dallas G. Hoover

Comprehensive Reviews in Food Science and Food Safety

Over the last 2 decades, a variety of bacteriocins, produced by bacteria that kill or inhibit the growth of other bacteria, have been identified and characterized biochemically and genetically. This...

A Bacterial Guanine Nucleotide Exchange Factor Activates ARF on <i>Legionella</i> Phagosomes

Hiroki Nagai, Jonathan C. Kagan, Xinjun Zhu +2

Science

The intracellular pathogen Legionella pneumophila subverts vesicle traffic in eukaryotic host cells to create a vacuole that supports replication. The dot/icm genes encode a protein secretion...

Effect of Reduced Dietary Sodium on Blood Pressure

Julian Midgley

JAMA

- Dietary sodium restriction for older hypertensive individuals might be considered, but the evidence in the normotensive population does not support current recommendations for universal dietary...

Towards a phenomenological definition of the term ‘gel’

Kristoffer Almdal, Jeppe C. Dyre, Søren Hvidt +1

Polymer Gels and Networks

Analysis of the multitrait-multimethod matrix by confirmatory factor analysis.

David A. Kenny, Deborah A. Kashy

Psychological Bulletin

The multitrait-multimethod (MTMM) matrix permits examination of the convergent and discriminant validity of psychological measures. Estimation using confirmatory factor analysis (CFA), the...

The Biochemical Functions of Ascorbic Acid

Sasha Englard, Sam Seifter

Annual Review of Nutrition

SCOPE OF THIS REVIEW . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 365 BIOSYNTHESIS AND...

The Enzymatic Oxidation of Pyridoxine and Pyridoxamine Phosphates

Hiroshi Wada, Esmond E. Snell

Journal of Biological Chemistry

A review of modern and conventional extraction techniques and their applications for extracting phytochemicals from plants

Bitwell Chibuye, Indra Sen Singh, Luke Chimuka +1

Scientific African

For centuries, phytochemicals have been of immense value to communities worldwide. These metabolites have been used in healthcare systems as medicines to treat various diseases. Further,...

Taste buds: cells, signals and synapses

Stephen D. Roper, Nirupa Chaudhari

Nature reviews. Neuroscience

The Global Hidden Hunger Indices and Maps: An Advocacy Tool for Action

Sumithra Muthayya, Jee Hyun Rah, Jonathan D. Sugimoto +3

PLoS ONE

The unified global efforts to mitigate the high burden of vitamin and mineral deficiency, known as hidden hunger, in populations around the world are crucial to the achievement of most of the...

The Consequence of Tree Pests and Diseases for Ecosystem Services

Ian L. Boyd, Peter H. Freer-Smith, Christopher A. Gilligan +1

Science

Trees and forests provide a wide variety of ecosystem services in addition to timber, food, and other provisioning services. New approaches to pest and disease management are needed that take into...

Real men don’t eat (vegetable) quiche: Masculinity and the justification of meat consumption.

Hank Rothgerber

Psychology of Men & Masculinity

As arguments become more pronounced that meat consumption harms the environment, public health, and animals, meat eaters should experience increased pressure to justify their behavior. Results of a...

Effects of oregano, carvacrol and thymol on Staphylococcus aureus and Staphylococcus epidermidis biofilms

Antonia Nostro, Andrea Sudano Roccaro, Giuseppe Bisignano +6

Journal of Medical Microbiology

The aim of this study was to evaluate the effect of oregano essential oil, carvacrol and thymol on biofilm-grown Staphylococcus aureus and Staphylococcus epidermidis strains, as well as the effects...

Global Dissemination of <i>Vibrio parahaemolyticus</i> Serotype O3:K6 and Its Serovariants

G. Balakrish Nair, Thandavarayan Ramamurthy, Sujit Bhattacharya +3

Clinical Microbiology Reviews

Vibrio parahaemolyticus is recognized as a cause of food-borne gastroenteritis, particularly in the Far East, where raw seafood consumption is high. An unusual increase in admissions of V....

Major Structural Differences and Novel Potential Virulence Mechanisms from the Genomes of Multiple Campylobacter Species

Derrick E. Fouts, Emmanuel F. Mongodin, Robert E. Mandrell +18

PLoS Biology

Sequencing and comparative genome analysis of four strains of Campylobacter including C. lari RM2100, C. upsaliensis RM3195, and C. coli RM2228 has revealed major structural differences that are...

Molecular Analysis of the Copper-Transporting Efflux System CusCFBA of <i>Escherichia coli</i>

Sylvia Franke, Gregor Grass, Christopher Rensing +1

Journal of Bacteriology

The cus determinant of Escherichia coli encodes the CusCFBA proteins that mediate resistance to copper and silver by cation efflux. CusA and CusB were essential for copper resistance, and CusC and...

Microbes from raw milk for fermented dairy products

Jan Wouters, Eman Ayad, Jeroen Hugenholtz +1

International Dairy Journal

Viability of yoghurt and probiotic bacteria in yoghurts made from commercial starter cultures

R. I. Dave, Nagendra P. Shah

International Dairy Journal

Dietary Intake of Marine n-3 Fatty Acids, Fish Intake, and the Risk of Coronary Disease among Men

Alberto Ascherio, Eric B. Rimm, Meir J. Stampfer +2

New England Journal of Medicine

Although the possibility of residual confounding by unmeasured factors cannot be entirely excluded, these data suggest that increasing fish intake from one to two servings per week to five to six...

A revisit to the three‐dimensional structure of B‐type starch

Anne Imberty, Serge Pérez

Biopolymers

Abstract A new three‐dimensional structure of B‐starch is proposed in which the unit cell contains 12 glucose residues located in two left‐handed, parallel‐stranded double helices packed in a...

Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol

Des R. Richardson, Darius J.R. Lane, E. Becker +5

Proceedings of the National Academy of Sciences

The mitochondrion is well known for its key role in energy transduction. However, it is less well appreciated that it is also a focal point of iron metabolism. Iron is needed not only for heme and...

Mechanisms underlying the cardioprotective effects of omega-3 polyunsaturated fatty acids

Yuriko Adkins, Darshan S. Kelley

The Journal of Nutritional Biochemistry

Stenotrophomonas maltophilia: an emerging opportunist human pathogen

W J Looney, Masashi Narita, Kathrin Mühlemann

The Lancet Infectious Diseases

Kinetic Modeling of Food Quality: A Critical Review

M.A.J.S. van Boekel

Comprehensive Reviews in Food Science and Food Safety

ABSTRACT: This article discusses the possibilities to study relevant quality aspects of food, such as color, nutrient content, and safety, in a quantitative way via mathematical models. These quality...

The Independent cue and cusSystems Confer Copper Tolerance during Aerobic and Anaerobic Growth inEscherichia coli

F. Wayne Outten, David L. Huffman, Jeremy A. Hale +1

Journal of Biological Chemistry

Copper is essential but can be toxic even at low concentrations. Coping with this duality requires multiple pathways to control intracellular copper availability. Three copper-inducible promoters,...

Oxidative stress and glycemic regulation

Antonio Ceriello

Metabolism

Nomenclature in evaluation of analytical methods including detection and quantification capabilities1Adapted from the International Union of Pure and Applied Chemistry (IUPAC) document “Nomenclature in Evaluation of Analytical Methods including Detection and Quantification Capabilities”, which originally appeared in Pure and Applied Chemistry, 67 1699–1723 (1995) © 1995 IUPAC. Republication permission granted by IUPAC.1

Lloyd A. Currie

Analytica Chimica Acta

Nutritional and Functional Characteristics of Whey Proteins in Food Products

J.N. de Wit

Journal of Dairy Science

Whey proteins are well known for their high nutritional value and versatile functional properties in food products. Estimates of the worldwide production of whey indicate that about 700,000 tonnes of...

Thrombolytic Therapy: Current Status

Victor J. Marder, Sol Sherry

New England Journal of Medicine

ONE decade after the Food and Drug Administration approved the plasminogen activators streptokinase and urokinase, thrombolytic therapy is no longer a novel approach to the treatment of thrombotic...

Hybridization of Crop Plants

ASSA, CSSA and SSSA

An experimental study of the mechanism of action of <i>vibrio choleræ</i> on the intestinal mucous membrane

S. N. De, D. N. Chatterje

The Journal of Pathology and Bacteriology

ESPEN micronutrient guideline

Mette M. Berger, Alan Shenkin, Anna Schweinlin +13

Clinical Nutrition

Nutritional recommendations for CoVID-19 quarantine

Giovanna Muscogiuri, Luigi Barrea, Silvia Savastano +1

European Journal of Clinical Nutrition

Zinc status is associated with inflammation, oxidative stress, lipid, and glucose metabolism

J. Olechnowicz, Alexey A. Tinkov, Andrey A. Skalny +1

The Journal of Physiological Sciences

A number of studies have reported that zinc plays a substantial role in the development of metabolic syndrome, taking part in the regulation of cytokine expression, suppressing inflammation, and is...

Early Childhood Developmental Status in Low- and Middle-Income Countries: National, Regional, and Global Prevalence Estimates Using Predictive Modeling

Dana Charles McCoy, Evan D. Peet, Majid Ezzati +5

PLoS Medicine

The number of children globally failing to reach their developmental potential remains large. Additional research is needed to identify the specific causes of poor developmental outcomes in diverse...

Legionnaires' disease

Burke A. Cunha, Almudena Burillo, Emilio Bouza

The Lancet

Unpacking Postharvest Losses in Sub-Saharan Africa: A Meta-Analysis

Hippolyte Affognon, Christopher Mutungi, Pascal C. Sanginga +1

World Development

Reducing postharvest losses (PHL) is a key pathway to food and nutrition security in sub-Saharan Africa. However, knowledge of PHL magnitudes is limited. A meta-analysis has been conducted to expose...

A new framework to enhance the interpretation of external validation studies of clinical prediction models

Thomas P. A. Debray, Yvonne Vergouwe, Hendrik Koffijberg +3

Journal of Clinical Epidemiology

The proposed framework enhances the interpretation of findings at external validation of prediction models.

Lipid Mediators in the Resolution of Inflammation

Charles N. Serhan, Nan Chiang, Jesmond Dalli +1

Cold Spring Harbor Perspectives in Biology

Mounting of the acute inflammatory response is crucial for host defense and pivotal to the development of chronic inflammation, fibrosis, or abscess formation versus the protective response and the...

Eugenol—From the Remote Maluku Islands to the International Market Place: A Review of a Remarkable and Versatile Molecule

Guy Kamatou, Ilze Vermaak, Alvaro Viljoen

Molecules

Eugenol is a major volatile constituent of clove essential oil obtained through hydrodistillation of mainly Eugenia caryophyllata (=Syzygium aromaticum) buds and leaves. It is a remarkably versatile...