Research Library

Multi-targeted therapy of cancer by omega-3 fatty acids

Isabelle M. Berquin, Iris J. Edwards, Yong Q. Chen

Cancer Letters

Antimicrobial susceptibilities of Lactobacillus, Pediococcus and Lactococcus human isolates and cultures intended for probiotic or nutritional use

Ingo Klare, Carola Konstabel, Guido Werner +7

Journal of Antimicrobial Chemotherapy

Finding of acquired resistance genes in isolates intended for probiotic or nutritional use highlights the importance of antimicrobial susceptibility testing in documenting the safety of commercial...

Anti-inflammation activities of essential oil and its constituents from indigenous cinnamon (Cinnamomum osmophloeum) twigs

Yu‐Tang Tung, Meng-Thong Chua, Sheng‐Yang Wang +1

Bioresource Technology

Antibacterial Properties and Major Bioactive Components of Cinnamon Stick (<i>Cinnamomum burmannii</i>):  Activity against Foodborne Pathogenic Bacteria

Bin Shan, Yi‐Zhong Cai, John D. Brooks +1

Journal of Agricultural and Food Chemistry

Cinnamomum burmannii Blume (cinnamon stick) from Indonesia is a little-investigated spice. In this study, the antibacterial activity, minimum inhibitory concentration (MIC), and minimum bactericidal...

Inferring the Evolutionary History of Vibrios by Means of Multilocus Sequence Analysis

Tomoo Sawabe, Kumiko Kita-Tsukamoto, Fabiano L. Thompson

Journal of Bacteriology

We performed the first broad study aiming at the reconstruction of the evolutionary history of vibrios by means of multilocus sequence analysis of nine genes. Overall, 14 distinct clades were...

Quantification of condensed tannins by precipitation with methyl cellulose: development and validation of an optimised tool for grape and wine analysis

Caroline J. Sarneckis, Robert G. Dambergs, Patrik R. Jones +3

Australian Journal of Grape and Wine Research

A precipitation assay is presented that enables tannin measurement in matrices of red wine, 50% ethanol grape extract and aqueous tannin solutions. By exploiting the polysaccharide polymer methyl...

Selenium: From cancer prevention to DNA damage

Lucia Letavayová, Viera Vlčková, Jela Brozmanová

Toxicology

Polyunsaturated fatty acids of marine origin induce adiponectin in mice fed a high-fat diet

Pavel Flachs, Vidya Mohamed‐Ali, Olga Horakova +5

Diabetologia

A metaanalysis of treatment outcomes of early enteral versus early parenteral nutrition in hospitalized patients*

John Victor Peter, John L. Moran, Jennie Phillips-Hughes

Critical Care Medicine

There was no mortality effect with the type of nutritional supplementation. Although early EN significantly reduced complication rates, this needs to be interpreted in the light of missing data and...

Long-chain conversion of [13C]linoleic acid and α-linolenic acid in response to marked changes in their dietary intake in men

Nahed Hussein, Eric Ah-Sing, Paul Wilkinson +3

Journal of Lipid Research

We studied the long-chain conversion of [U-13C]alpha-linolenic acid (ALA) and linoleic acid (LA) and responses of erythrocyte phospholipid composition to variation in the dietary ratios of 18:3n-3...

Breastfeeding and risk of inflammatory bowel disease: a systematic review with meta-analysis

Eyal Klement, Regev V Cohen, Jonathan Boxman +2

American Journal of Clinical Nutrition

Rheological properties of rice dough for making rice bread

Hema P. Sivaramakrishnan, B. Senge, P. K. Chattopadhyay

Journal of Food Engineering

The Catabolism of Amino Acids to Long Chain and Complex Alcohols in Saccharomyces cerevisiae

J. Richard Dickinson, L. Eshantha J. Salgado, M. J. E. Hewlins

Journal of Biological Chemistry

The catabolism of phenylalanine to 2-phenylethanol and of tryptophan to tryptophol were studied by (13)C NMR spectroscopy and gas chromatography-mass spectrometry. Phenylalanine and tryptophan are...

The genome sequence of <i>Clostridium tetani</i> , the causative agent of tetanus disease

Holger Brüggemann, Sebastian Bäumer, W. Florian Fricke +8

Proceedings of the National Academy of Sciences

Tetanus disease is one of the most dramatic and globally prevalent diseases of humans and vertebrate animals, and has been reported for over 24 centuries. The manifestation of the disease, spastic...

Fate of <i>Escherichia coli</i> O157:H7 in Manure-Amended Soil

Xiuping Jiang, Jennie Morgan, Michael P. Doyle

Applied and Environmental Microbiology

Escherichia coli O157:H7 cells survived for up to 77, >226, and 231 days in manure-amended autoclaved soil held at 5, 15, and 21 degrees C, respectively. Pathogen populations declined more rapidly in...

Surface characterization of four industrial spray-dried dairy powders in relation to chemical composition, structure and wetting property

Esther H.‐J. Kim, Xiao Dong Chen, David Pearce

Colloids and Surfaces B Biointerfaces

Identification of G protein‐coupled receptor genes from the human genome sequence

Shigeki Takeda, Shiro Kadowaki, Tatsuya Haga +2

FEBS Letters

We have identified novel G protein-coupled receptors (GPCRs) with no introns in the coding region from the human genome sequence: 322 olfactory receptors; 22 taste receptors; 128 registered GPCRs for...

Fish Consumption and Depressive Symptoms in the General Population in Finland

Antti Tanskanen, Joseph R. Hibbeln, Jaakko Tuomilehto +5

Psychiatric Services

Fish contains high concentrations of omega-3 polyunsaturated fatty acids. Several studies have reported depletions of omega-3 fats among depressed patients, and a cross-national comparison has...

The protective role of selenium on genetic damage and on cancer

Karam El‐Bayoumy

Mutation research. Fundamental and molecular mechanisms of mutagenesis

Hepatic response to sepsis: Interaction between coagulation and inflammatory processes

Jean-François Dhainaut, Nathalie Marin, Alexandre Mignon +1

Critical Care Medicine

In sepsis, the liver participates in host defense and tissue repair through hepatic cell cross-talk that controls most of the coagulation and inflammatory processes. When this control is not...

Divergent Roles of SHP-2 in ERK Activation by Leptin Receptors

Christian Bjørbæk, Ryan M. Buchholz, Sarah M. Davis +6

Journal of Biological Chemistry

The protein tyrosine phosphatase SHP-2 has been proposed to serve as a regulator of leptin signaling, but its specific roles are not fully examined. To directly investigate the role of SHP-2, we...

The Global Impact of Neonatal Infection

Barbara J. Stoll

Clinics in Perinatology

Management of Venous Thromboembolism

Jeffrey S. Ginsberg

New England Journal of Medicine

Venous thromboembolism, which includes deep-vein thrombosis (usually involving leg veins) and pulmonary embolism, is a common cause of death. Treatment of affected patients reduces the incidence of...

Influence of amylose content on starch films and foams

Denis Lourdin, Guy Della Valle, Paul Colonna

Carbohydrate Polymers

Cattle as a possible source of verocytotoxin-producing<i>Escherichia coli</i>O157 infections in man

P. A. Chapman, C. A. Siddons, Dominic Wright +3

Epidemiology and Infection

In May-June 1992 cases of infection with verocytotoxin-producing (VT+) Escherichia coli O157 in South Yorkshire could have been associated with prior consumption of beef from a local abattoir. During...

Immunologic effects of national cholesterol education panel step-2 diets with and without fish-derived N-3 fatty acid enrichment.

S N Meydani, Alice H. Lichtenstein, Steve Cornwall +5

Journal of Clinical Investigation

Reductions in dietary fat, saturated fat, and cholesterol have been recommended to reduce the risk of heart disease in our society. The effects of these modifications on human cytokine production and...

Identification of multiple metal regulatory elements in mouse metallothionein-I promoter by assaying synthetic sequences

Gary W. Stuart, Peter F. Searle, Richard D. Palmiter

Nature

Characteristics of carbohydrate degradation and the rate‐limiting step in anaerobic digestion

Tatsuya Noike, Ginro Endo, Juu‐En Chang +2

Biotechnology and Bioengineering

The characteristics of the degradation of cellulose, soluble starch, and glucose in the acidogenic phase and the effects of the substrate loading rate and biological solids retention time on the...

Dietary requirements and functions of α-linolenic acid in animals

J. Tinoco

Progress in Lipid Research

Crypts Are the Site of Intestinal Fluid and Electrolyte Secretion

Michael J. Welsh, Philip L. Smith, Michael Fromm +1

Science

The site of adenosine 3',5'-monophosphate-mediated fluid and electrolyte secretion across mammalian large intestine was found to be the crypts of Lieberkühn by means of two techniques. First, the...

Hydrogen peroxide metabolism in human monocytes during differentiation in vitro.

Akira Nakagawara, Carl Nathan, Zanvil A. Cohn

Journal of Clinical Investigation

The capacity of human blood monocytes to secrete hydrogen peroxide (H2O2) and superoxide (O2-) was measured as the cells differentiated during 4 wk of culture. Morphologic transformation of monocytes...

Sequestration of Plant Natural Products by Insects

Sean S. Duffey

Annual Review of Entomology

Although the insect circulatory system is involved in a multitude of vital physiological processes, it has gone grossly understudied. This review highlights this critical physiological system by...

Mucosal and Glandular Distribution of Immunoglobulin Components: Differential Localization of Free and Bound SC in Secretory Epithelial Cells

Per Brandtzæg

The Journal of Immunology

Abstract Immunohistochemistry of saline-extracted human glandular tissue revealed that secretory epithelial cells contain membrane-associated IgA and secretory component (SC). Free SC alone was...

TRPM7 kinase-mediated immunomodulation in macrophage plays a central role in magnesium ion-induced bone regeneration

Wei Qiao, Karen H.M. Wong, Jie Shen +14

Nature Communications

Despite the widespread observations on the osteogenic effects of magnesium ion (Mg²⁺), the diverse roles of Mg²⁺ during bone healing have not been systematically dissected....

A review of drying methods for improving the quality of dried herbs

Grant Thamkaew, Ingegerd Sjöholm, Federico Gómez Galindo

Critical Reviews in Food Science and Nutrition

A large number of herb-drying studies have been conducted in recent decades and several herb-drying techniques have been introduced. However, the quality of commercial dried herbs is still lower than...

<i>Salmonella</i> persisters undermine host immune defenses during antibiotic treatment

Daphne A. C. Stapels, Peter W. S. Hill, Alexander J. Westermann +6

Science

Many bacterial infections are hard to treat and tend to relapse, possibly due to the presence of antibiotic-tolerant persisters. In vitro, persister cells appear to be dormant. After uptake of...

Enumeration of probiotic strains: Review of culture-dependent and alternative techniques to quantify viable bacteria

Catherine Davis

Journal of Microbiological Methods

Probiotics are live microorganisms which, when administered in adequate amounts, confer a health benefit on the host. Standard culture techniques are commonly used to quantify probiotic strains, but...

Japanese 2011 guidelines for prevention and treatment of osteoporosis—executive summary

Hajime Orimo, Toshitaka Nakamura, Takayuki Hosoi +12

Archives of Osteoporosis

The essential points of the Japanese practice guidelines on osteoporosis were translated into English for the first time. It is hoped that the content of the guidelines becomes known throughout the...

Analysis of starch amylolysis using plots for first-order kinetics

Peter Butterworth, Frederick J. Warren, Terri Grassby +2

Carbohydrate Polymers

Towards Establishing Dietary Reference Intakes for Eicosapentaenoic and Docosahexaenoic Acids

William S. Harris, Dariush Mozaffarian, Michael Lefevre +7

Journal of Nutrition

EPA but Not DHA Appears To Be Responsible for the Efficacy of Omega-3 Long Chain Polyunsaturated Fatty Acid Supplementation in Depression: Evidence from a Meta-Analysis of Randomized Controlled Trials

Julian G Martins

Journal of the American College of Nutrition

The current meta-analysis provides evidence that EPA may be more efficacious than DHA in treating depression. However, owing to the identified limitations of the included studies, larger,...

Oxidative Stress as a Mediator of Cardiovascular Disease

Maqsood M. Elahi, Yu Xiang George Kong, Bashir M. Matata

Oxidative Medicine and Cellular Longevity

During physiological processes molecules undergo chemical changes involving reducing and oxidizing reactions. A molecule with an unpaired electron can combine with a molecule capable of donating an...

Water sorption isotherms and glass transition temperature of spray dried tomato pulp

Athanasia M. Goula, Thodoris D. Karapantsios, Dimitris S. Achilias +1

Journal of Food Engineering

Pomegranate juice decreases amyloid load and improves behavior in a mouse model of Alzheimer's disease

Richard E. Hartman, Aartie Shah, Anne M. Fagan +5

Neurobiology of Disease

Magnesium Intake and Incidence of Metabolic Syndrome Among Young Adults

Ka He, Kiang Liu, Martha L. Daviglus +5

Circulation

Our findings suggest that young adults with higher magnesium intake have lower risk of development of metabolic syndrome.

Long-chain<i>n</i>−3 PUFA: plant<i>v</i>. marine sources

Christine M. Williams, Graham C. Burdge

Proceedings of The Nutrition Society

Increasing recognition of the importance of the long-chain n-3 PUFA, EPA and DHA, to cardiovascular health, and in the case of DHA to normal neurological development in the fetus and the newborn, has...

Radioprotection by plant products: present status and future prospects

Rajesh Arora, Damodar Gupta, Raman Chawla +7

Phytotherapy Research

The development of radioprotective agents has been the subject of intense research in view of their potential for use within a radiation environment, such as space exploration, radiotherapy and even...

Screening of Chemical Composition and Antifungal and Antioxidant Activities of the Essential Oils from Three Turkish <i>Artemisia </i>Species

Şaban Kordalı, Ahmet Çakır, Ahmet Mavi +2

Journal of Agricultural and Food Chemistry

The compositions of essential oils isolated from the aerial parts of Artemisia absinthium, Artemisia santonicum, and Artemisia spicigera by hydrodistillation were analyzed by GC-MS, and a total of...

Antifungal activity of <i>Thymus</i> oils and their major compounds

Cidália Pina‐Vaz, Acácio G. Rodrigues, Eugénia Pinto +6

Journal of the European Academy of Dermatology and Venereology

The increasing recognition and importance of fungal infections, the difficulties encountered in their treatment and the increase in resistance to antifungals have stimulated the search for...