Research Library

Inflammation in the developing human intestine: A possible pathophysiologic contribution to necrotizing enterocolitis

N. Nanda Nanthakumar, Robert D. Fusunyan, Ian R. Sanderson +1

Proceedings of the National Academy of Sciences

Necrotizing enterocolitis (NEC), a major cause of morbidity and mortality in premature infants, occurs after the introduction of oral feedings in conjunction with initial bacterial colonization of...

Typhoid fever in children aged less than 5 years

Anju Sinha, Sunil Sazawal, Ramesh Kumar +7

The Lancet

A new class of wine pigments generated by reaction between pyruvic acid and grape anthocyanins

Hélène Fulcrand, Carime Benabdeljalil, Jacques Rigaud +2

Phytochemistry

Bacterial translocation from the gastrointestinal tract

Rodney D. Berg

Trends in Microbiology

Detection of interleukin 8 and tumor necrosis factor in normal humans after intravenous endotoxin: the effect of antiinflammatory agents.

G. Daniel Martich, Robert L. Danner, M. Ceska +1

The Journal of Experimental Medicine

Interleukin 8 (IL-8), a potent activator of neutrophils, may be important in the early host response to serious Gram-negative infections. IL-8 was measured with other acute phase cytokines (tumor...

Identification of the carbohydrate receptor for Shiga toxin produced by Shigella dysenteriae type 1.

Alf A. Lindberg, J E Brown, Nicklas Strömberg +3

Journal of Biological Chemistry

The binding of Shiga toxin isolated from the bacterium Shigella dysenteriae type 1 to a series of glycolipids and to cells or cell homogenates has been studied. Bound toxin was detected using either...

Campylobacter pyloridis and Gastritis: Association with Intercellular Spaces and Adaptation to an Environment of Mucus as Important Factors in Colonization of the Gastric Epithelium

Stuart L. Hazell, Adrian V. Lee, Lynette Brady +1

The Journal of Infectious Diseases

Stomach biopsy specimens from greater than 40 individuals with Campylobacter pyloridis-associated gastritis were examined by light and electron microscopy. The bacteria were consistently seen in two...

A polymer physico-chemical approach to the study of commercial starch hydrolysis products (SHPs)

Harry Levine, Louise Slade

Carbohydrate Polymers

Selenium, Selenoproteins and Viral Infection

Olivia Guillin, Caroline Vindry, Théophile Ohlmann +1

Nutrients

Reactive oxygen species (ROS) are frequently produced during viral infections. Generation of these ROS can be both beneficial and detrimental for many cellular functions. When overwhelming the...

Formation of Food‐Grade Nanoemulsions Using Low‐Energy Preparation Methods: A Review of Available Methods

Jennifer Komaiko, David Julian McClements

Comprehensive Reviews in Food Science and Food Safety

There is considerable interest in the production of emulsions and nanoemulsions using low-energy methods due to the fact they are simple to implement and no expensive equipment is required. In this...

<i>Salmonella enterica</i>: Survival, Colonization, and Virulence Differences among Serovars

Ana Andino, Irene Hanning

The Scientific World JOURNAL

Data indicate that prevalence of specific serovars of Salmonella enterica in human foodborne illness is not correlated with their prevalence in feed. Given that feed is a suboptimal environment for...

Sweet taste receptors in rat small intestine stimulate glucose absorption through apical GLUT2

Oliver J. Mace, Julie Affleck, Nick Patel +1

The Journal of Physiology

Natural sugars and artificial sweeteners are sensed by receptors in taste buds. T2R bitter and T1R sweet taste receptors are coupled through G-proteins, alpha-gustducin and transducin, to activate...

A Method for Estimating the Nature and Relative Proportions of Amorphous, Single, and Double-Helical Components in Starch Granules by¹³C CP/MAS NMR

Ihwa Tan, Bernadine M. Flanagan, Peter J. Halley +2

Biomacromolecules

An improved method to analyze the 13C NMR spectra of native starches, which considers the contribution of the V-type conformation and the nature of the amorphous component, has been developed. Starch...

Regulation of Legionella Phagosome Maturation and Infection through Flagellin and Host Ipaf

Amal O. Amer, Luigi Franchi, Thirumala‐Devi Kanneganti +8

Journal of Biological Chemistry

Legionella pneumophila is an intracellular bacterium that causes an acute form of pneumonia called Legionnaires' disease. After infection of human macrophages, the Legionella-containing phagosome...

Dietary intake of trans fatty acids and systemic inflammation in women

Dariush Mozaffarian, Tobias Pischon, Susan E. Hankinson +4

American Journal of Clinical Nutrition

Subtle Acquired Renal Injury as a Mechanism of Salt-Sensitive Hypertension

Richard J. Johnson, Jaime Herrera-Acosta, George F. Schreiner +1

New England Journal of Medicine

Salt sensitivity is present in about half of people with essential hypertension; decreasing salt intake ameliorates the hypertension. This review provides an explanation of how initially subtle renal...

The INTERSALT Study: background, methods, findings, and implications

J. Stamler

American Journal of Clinical Nutrition

A randomised prospective comparison of percutaneous endoscopic gastrostomy and nasogastric tube feeding after acute dysphagic stroke

Bernard Norton, M Homer-Ward, Mark Donnelly +2

BMJ

This study indicates that early gastrostomy tube feeding is greatly superior to nasogastric tube feeding and should be the nutritional treatment of choice for patients with acute dysphagic stroke.

BIOLOGICAL CONTROL OF CHESTNUT BLIGHT IN EUROPE

U. Heiniger, Daniel Rigling

Annual Review of Phytopathology

&lt;em&gt;Cryphonectria parasitica &lt;/em&gt;(Murr.) Barr. (Syn. &lt;em&gt;Endothia parasitica&lt;/em&gt; (Murr.) And. &amp;amp; And.), the causal agent of chestnut blight, is a fungal pathogen of...

The role of polyunsaturated fatty acids in fish

Michael V. Bell, R. J. Henderson, J. R. Sargent

Comparative Biochemistry and Physiology Part B Comparative Biochemistry

INCREASED SALT APPETITE IN ADRENALECTOMIZED RATS

Curt P. Richter

American Journal of Physiology-Legacy Content

Update of the list of QPS‐recommended biological agents intentionally added to food or feed as notified to EFSA 13: suitability of taxonomic units notified to EFSA until September 2020

EFSA Panel on Biological Hazards (BIOHAZ), Kostas Koutsoumanis, Ana Allende +25

EFSA Journal

The qualified presumption of safety (QPS) approach was developed to provide a regularly updated generic pre-evaluation of the safety of biological agents, intended for addition to food or feed, to...

Fruit and vegetable waste management: Conventional and emerging approaches

Irene Esparza, Nerea Jiménez‐Moreno, Fernando Bimbela +2

Journal of Environmental Management

Validation of Analytical Procedures: Methodology

Sarfaraz K. Niazi

Lactic Acid Bacteria Antimicrobial Compounds: Characteristics and Applications

Janaína Alves dos Reis, Aline Teodoro de Paula, Sabrina Neves Casarotti +1

Food Engineering Reviews

Tracing the Source of Campylobacteriosis

Daniel J. Wilson, Edith Gabriel, A. J. H. Leatherbarrow +7

PLoS Genetics

Campylobacter jejuni is the leading cause of bacterial gastro-enteritis in the developed world. It is thought to infect 2-3 million people a year in the US alone, at a cost to the economy in excess...

Variation in virulence among clades of <i>Escherichia coli</i> O157:H7 associated with disease outbreaks

Shannon D. Manning, Alifiya S. Motiwala, A. Cody Springman +11

Proceedings of the National Academy of Sciences

Escherichia coli O157:H7, a toxin-producing food and waterborne bacterial pathogen, has been linked to large outbreaks of gastrointestinal illness for more than two decades. E. coli O157 causes a...

Clinical, immunological, anti-inflammatory and antioxidant roles of zinc

Ananda S. Prasad

Experimental Gerontology

Management of severe acute malnutrition in children

Steve Collins, Nicky Dent, Paul Binns +3

The Lancet

Mechanism of protein stabilization by sugars during freeze-drying and storage: Native structure preservation, specific interaction, and/or immobilization in a glassy matrix?

Liuquan Chang, Deanna Shepherd, Joanna Sun +4

Journal of Pharmaceutical Sciences

The SmtB/ArsR family of metalloregulatory transcriptional repressors: structural insights into prokaryotic metal resistance

Laura S. Busenlehner, Mario A. Pennella, David Giedroc

FEMS Microbiology Reviews

The SmtB/ArsR family of prokaryotic metalloregulatory transcriptional repressors represses the expression of operons linked to stress-inducing concentrations of di- and multivalent heavy metal ions....

Animal models of infections: enteritis versus typhoid fever

Renato L. Santos, Shuping Zhang, Renée M. Tsolis +3

Microbes and Infection

HYBRID POPULATIONS SELECTIVELY FILTER GENE INTROGRESSION BETWEEN SPECIES

Gregory D. Martinsen, Thomas G. Whitham, Richard J. Turek +1

Evolution

Hybrids have long been recognized as a potential pathway for gene flow between species that can have important consequences for evolution and conservation biology. However, few studies have...

Direct profiling of the yeast dynamics in wine fermentations

Luca Cocolin, Linda F. Bisson, David A. Mills

FEMS Microbiology Letters

We present a method to directly characterize the yeast diversity present in wine fermentations by employing denaturing gradient gel electrophoresis (DGGE) of polymerase chain reaction (PCR)-amplified...

Non-Places: Introduction to an Anthropology of Supermodernity

David Harvie

Capital & Class

The sensitivity of a pinhole collimator for gamma ray imaging in nuclear medicine is dependent on the angle of incidence of the gamma rays. The effect of penetration near the pinhole aperture on...

ZnT-2, a mammalian protein that confers resistance to zinc by facilitating vesicular sequestration.

Richard D. Palmiter, Toby B. Cole, Seth D. Findley

The EMBO Journal

Elucidation of the Primary and Three-Dimensional Structure of the Uterotonic Polypeptide Kalata B1

Olav Saether, David J. Craik, Iain D. Campbell +3

Biochemistry

The amino acid sequence and structure of a uterotonic polypeptide extracted from the African plant Oldenlandia affinis DC have been determined. The peptide, kalata B1, consists of 29 amino acid...

TolC, an Escherichia coli outer membrane protein required for hemolysin secretion.

C Wandersman, Philippe Delepelaire

Proceedings of the National Academy of Sciences

Secretion of Escherichia coli alpha-hemolysin into the medium does not require the cleavage of an N-terminal signal peptide. The specific secretion apparatus was shown to consist of two proteins,...

Percutaneous endoscopic gastrostomy: a nonoperative technique for feeding gastrostomy

Jeffrey L. Ponsky, Michael W.L. Gauderer

Gastrointestinal Endoscopy

Fractionation of human-serum proteins by gel filtration

Per Flodin, Johan Killander

Biochimica et Biophysica Acta

Efficacy and safety of setmelanotide, an MC4R agonist, in individuals with severe obesity due to LEPR or POMC deficiency: single-arm, open-label, multicentre, phase 3 trials

Karine Clément, Erica L T van den Akker, Jesús Argente +27

The Lancet Diabetes & Endocrinology

Recent advances in the extraction of bioactive compounds with subcritical water: A review

Jixian Zhang, Chaoting Wen, Haihui Zhang +2

Trends in Food Science & Technology

Urolithins, the rescue of “old” metabolites to understand a “new” concept: Metabotypes as a nexus among phenolic metabolism, microbiota dysbiosis, and host health status

Francisco A. Tómas‐Barberán, Antonio González‐Sarrías, Rocío Garcı́a-Villalba +4

Molecular Nutrition & Food Research

Urolithins are dibenzo[b,d]pyran-6-one derivatives that are produced by the human gut microbiota from ellagitannins and ellagic acid (EA). These metabolites are much better absorbed than their...

Superior antibacterial activity of nanoemulsion of Thymus daenensis essential oil against E. coli

Roya Moghimi, Lida Ghaderi, Hasan Rafati +2

Food Chemistry

Food security: the challenge of increasing wheat yield and the importance of not compromising food safety

Tanya Y. Curtis, Nigel G. Halford

Annals of Applied Biology

Current wheat yield and consumption is considered in the context of the historical development of wheat, from early domestication through to modern plant breeding, the Green Revolution and wheat's...

Human and Avian Extraintestinal Pathogenic <i>Escherichia coli</i> : Infections, Zoonotic Risks, and Antibiotic Resistance Trends

Melha Mellata

Foodborne Pathogens and Disease

Extraintestinal pathogenic Escherichia coli (ExPEC) constitutes ongoing health concerns for women, newborns, elderly, and immunocompromised individuals due to increased numbers of urinary tract...

Ultrasonic emulsification of food-grade nanoemulsion formulation and evaluation of its bactericidal activity

Vijayalakshmi Ghosh, Amitava Mukherjee, Natarajan Chandrasekaran

Ultrasonics Sonochemistry

Wheat bran: its composition and benefits to health, a European perspective

L. Stevenson, Frankie Phillips, Kathryn O’Sullivan +1

International Journal of Food Sciences and Nutrition

Wheat bran is a concentrated source of insoluble fibre. Fibre intakes are generally lower than recommendations. This paper reviews the physiological effects of wheat bran and the health benefits it...