Fluorine-functionalized magnetic covalent organic frameworks for the extraction of aflatoxin B1 and two precursors for the early warning in agricultural products.

Abstract

The monitoring of aflatoxin B1 (AFB1) precursors was a significant step to prevent the production of AFB1. In this research, a novel magnetic fluorinated covalent organic framework (F-COF@Fe3O4) was prepared for the extraction of AFB1 and its two precursors of sterigmatocystin (ST) and averantin (AVN). Multiple interactions (i.e., F-O, F-F, etc.) between F-COF and analytes were confirmed via the theoretical calculation and the instrument characterization, which brought desirable extraction capacity of F-COF@Fe3O4 towards three targets. Thus, a purification and preconcentration method was established for the determination of AFB1, ST and AVN with the linearity of 0.02-100 μg L-1 and LODs of 0.012-0.017 μg L-1. Through the application in real samples, results presented that extraction recoveries were 70.03-101.20 %, and matrix effects were 5.29-19.37 %. The applicability of this method opened a new avenue to early warn the production of AFB1 in agricultural products.