2024peer-reviewed41 citations
Urolithin A inhibits breast cancer progression via activating TFEB-mediated mitophagy in tumor macrophages
Bowen Zheng, Yuying Wang, Baian Zhou, Fengyuan Qian, Diya Liu, Danrong Ye +2 more
Journal of Advanced Research
Abstract
Our study elucidated the anti-breast cancer effect of UA from the perspective of tumor-associated macrophages. Specifically, TFEB is a crucial downstream target in macrophages.
Concepts
TFEBAutophagyCancer researchTumor microenvironmentMitophagyTumor promotionTumor necrosis factor alphaTumor progression