Effects of cocoa extract and a multivitamin on cognitive function: A randomized clinical trial
Laura D. Baker, JoAnn E. Manson, Stephen R. Rapp, Howard D. Sesso, Sarah A. Gaussoin, Sally A. Shumaker +1 more
Alzheimer s & Dementia
Abstract
COSMOS-Mind was a large simple pragmatic randomized clinical trial in older adults conducted by mail and telephone. The trial used a two-by-two factorial design to assess treatment effects of two different interventions within a single large study. We found no cognitive benefit of daily cocoa extract administration (containing 500 mg flavanols) for 3 years. Daily multivitamin-mineral (MVM) supplementation for 3 years improved global cognition, episodic memory, and executive function in older adults. The MVM benefit appeared to be greater for adults with cardiovascular disease.
Extracted Claims
3 claims extracted from this paper into the knowledge graph
multivitamin-mineral improves cognitive function
“Daily multivitamin-mineral (MVM) supplementation for 3 years improved global cognition, episodic memory, and executive function in older adults.”
multivitamin-mineral has greater benefit for cognitive function
“The MVM benefit appeared to be greater for adults with cardiovascular disease.”
cocoa extract has no effect on cognitive function
“We found no cognitive benefit of daily cocoa extract administration (containing 500 mg flavanols) for 3 years.”