Protective Effect of Mitophagy Regulated by mTOR Signaling Pathway in Liver Fibrosis Associated with Selenium
Lichun Qiao, Ziwei Guo, Haobiao Liu, Jiaxin Liu, Xue Lin, Huan Deng +5 more
Nutrients
Abstract
Mitophagy regulated by the mTOR signaling pathway plays a dual protective role on low-selenium inducing liver fibrosis and nano-selenium supplements preventing liver fibrosis. Mitochondrial energy metabolism plays an important role in these processes as well.
Concepts
MitophagyAutophagyPI3K/AKT/mTOR pathwayMitochondrionBiologyFibrosisCell biologyEndocrinology