Enzyme kinetic approach for mechanistic insight and predictions of in vivo starch digestibility and the glycaemic index of foods
Peter Butterworth, Balázs Bajka, Cathrina H. Edwards, Frederick J. Warren, Peter R. Ellis
Trends in Food Science & Technology
Abstract
This review shows how enzyme kinetic strategies can provide explanations for differences in digestion rate of different starchy foods. Michaelis-Menten and Log of Slope analyses provide kinetic parameters (e.g., <i>K</i> <sub><i>m</i></sub> and <i>k</i> <sub><i>cat</i></sub> <i>/K</i> <sub><i>m</i></sub> ) for evaluating catalytic efficiency and ease of digestibility of starch by α-amylase. Suitable kinetic methods maximise the information that can be obtained from <i>in vitro</i> work for predictions of starch digestion and glycaemic responses <i>in vivo</i>.
Extracted Claims
3 claims extracted from this paper into the knowledge graph
Michaelis-Menten and Log of Slope analyses provide kinetic parameters for evaluating catalytic efficiency and ease of digestibility of starch by α-amylase
“Michaelis-Menten and Log of Slope analyses provide kinetic parameters (e.g., K<sub>m</sub> and k<sub>cat</sub>/K<sub>m</sub>) for evaluating catalytic efficiency and ease of digestibility of starch by...”
enzyme kinetic strategies provide explanations for differences in digestion rate of different starchy foods
“This review shows how enzyme kinetic strategies can provide explanations for differences in digestion rate of different starchy foods.”
suitable kinetic methods maximize information that can be obtained from in vitro work for predictions of starch digestion and glycaemic responses in vivo
“Suitable kinetic methods maximise the information that can be obtained from in vitro work for predictions of starch digestion and glycaemic responses in vivo.”