2021peer-reviewed51 citations
Vitamin C Inhibits the Metabolic Changes Induced by Tet1 Insufficiency Under High Fat Diet Stress
Yangmian Yuan, Chengyu Liu, Xingrui Chen, Yuyan Sun, Mingrui Xiong, Yu Fan +4 more
Molecular Nutrition & Food Research
Abstract
The results reveal a novel function of Tet1 in obesity and provide a new mechanism for the beneficial role of vitamin C in metabolic diseases through enhanced Tet1 activity.
Concepts
EndocrinologyInternal medicineWhite adipose tissueDNA demethylationLipolysisVitaminFatty liverAdipose tissue