Drying of Pharmaceuticals: The Applicability of Spouted Beds
Ricardo Neves Marreto, José Teixeira Freire, Luís Alexandre Pedro de Freitas
Drying Technology
Abstract
ABSTRACT This study evaluates the performance of conventional spouted beds (CSB) with inert bodies in the drying of pharmaceutical pastes, based on the dry product quality. The powder obtained by drying annatto extracts shows properties comparable to one of the commercial products, indicating that the spouting is competitive with other industrial and lab-scale processes. The contents of bixin and caffeine in annatto and guarana dry powders demonstrated a strong dependence on the inlet air temperature. Also, the properties of indomethacin-containing microcapsules dried in CSB and spray dryers revealed that spouting is a promising technique to obtain pharmaceutical forms with unique drug release qualities.
Extracted Claims
1 claim extracted from this paper into the knowledge graph
spouted beds affects bixin and caffeine content in annatto and guarana dry powders
“The contents of bixin and caffeine in annatto and guarana dry powders demonstrated a strong dependence on the inlet air temperature.”