Failure of Nicotinic Acid to Prevent Nutritional Cytopenia in the Monkey.
Paul L. Day, William C. Langston, William J. Darby
Experimental Biology and Medicine
Abstract
Five monkeys were given a diet which experience had shown would produce anemia, leukopenia and death. Three of the monkeys received daily supplements of 10 mg, and 2 received 50 mg of nicotinic acid. The nicotinic acid did not prevent the cytopenia or prolong life. It is evident that this syndrome in the monkey is not analogous to black-tongue in dogs or pellagra in man. We wish to propose the designation "vitamin M" for the hitherto undifferentiated factor which prevents this nutritional cytopenia in the monkey.
Extracted Claims
1 claim extracted from this paper into the knowledge graph
Nicotinic acid does not prevent nutritional cytopenia in monkeys
“The nicotinic acid did not prevent the cytopenia or prolong life.”