Acetoxychavicol Acetate, an Antifungal Component of<i>Alpinia galanga</i><sup>1</sup>
Arne Janssen, J. Scheffer
Planta Medica
Abstract
The essential oils from fresh and dried rhizomes of ALPINIA GALANGA showed an antimicrobial activity against gram-positive bacteria, a yeast and some dermatophytes, using the agar overlay technique. The main components of the oils were also tested and terpinen-4-ol was found most active. An N-pentane/diethyl ether extract of dried rhizomes was active against TRICHOPHYTON MENTAGROPHYTES. 1'-Acetoxychavicol acetate, 1'-acetoxyeugenol acetate and 1'-hydroxychavicol acetate identified by MS and NMR were found in the antifungally active fractions obtained by LSC. Acetoxychavicol acetate was active against the seven fungi tested and its MIC value for dermatophytes ranged from 50 to 250 microg/ml. Dried sliced rhizomes contained 1.5% of this compound. The compound was not found in rhizomes of ALPINIA OFFICINARUM, ZINGIBER OFFICINALE and KAEMPFERIA GALANGA.
Extracted Claims
3 claims extracted from this paper into the knowledge graph
1'-acetoxychavicol acetate found in dried rhizomes of Alpinia galanga
“Dried sliced rhizomes contained 1.5% of this compound.”
1'-acetoxychavicol acetate not found in rhizomes of Alpinia officinarum, Zingiber officinale, and Kaempferia galanga
“The compound was not found in rhizomes of ALPINIA OFFICINARUM, ZINGIBER OFFICINALE and KAEMPFERIA GALANGA.”
acetoxychavicol acetate active against fungi
“Acetoxychavicol acetate was active against the seven fungi tested and its MIC value for dermatophytes ranged from 50 to 250 microg/ml.”