Correction of Essential Fatty Acid Deficiency in Newborn Infants by Cutaneous Application of Sunflower-Seed Oil
Zvi Friedman, Stephen J. Shochat, M.J. Maisels, Keith H. Marks, Edward L. Lamberth
PEDIATRICS
Abstract
Two newborn infants receiving long-term, fat-free parenteral nutrition developed essential fatty acid (EFA) deficiency. Biochemical evidence of EFA deficiency was documented in plasma, red blood cells, and adipose tissue and included a decrease in arachidonic and linoleic acids, an increase in 5,8,11-eicosatrienoic acid, palmitoleic and oleic acids and a trienoic/tetraenoic ratio of more than 0.4. Cutaneous application of sunflower-seed oil, a source rich in the essential fat linoleic acid, rapidly reversed the clinical and biochemical manifestations of deficiency in plasma.
Extracted Claims
1 claim extracted from this paper into the knowledge graph
sunflower-seed oil reverse clinical and biochemical manifestations of essential fatty acid (EFA) deficiency
“Cutaneous application of sunflower-seed oil, a source rich in the essential fat linoleic acid, rapidly reversed the clinical and biochemical manifestations of deficiency in plasma.”