Gastroprotective and anti-inflammatory properties of green lipped mussel (Perna canaliculus) preparation.
K. D. Rainsford, M. W. Whitehouse
PubMed
Abstract
Freeze-dried powdered preparations of whole (i.e. without shell) green-lipped mussel (Perna canaliculus) from New Zealand given orally to rats showed some modest anti-inflammatory activity (carrageenan paw oedema). This material strikingly reduced the gastric ulcerogenicity of several non-steroid anti-inflammatory drugs in rats and pigs. The gastroprotective activity in rats was primarily associated with particular lipid fractions, which exhibited differential protective activity against acetylsalicylic acid on the one hand and indometacin on the other.
Extracted Claims
2 claims extracted from this paper into the knowledge graph
green-lipped mussel (Perna canaliculus) preparation reduced gastric ulcerogenicity of non-steroid anti-inflammatory drugs
“This material strikingly reduced the gastric ulcerogenicity of several non-steroid anti-inflammatory drugs in rats and pigs.”
lipid fractions from green-lipped mussel (Perna canaliculus) exhibited differential protective activity against acetylsalicylic acid and indometacin
“The gastroprotective activity in rats was primarily associated with particular lipid fractions, which exhibited differential protective activity against acetylsalicylic acid on the one hand and indome...”