Research Library

Identification of the gene for vitamin K epoxide reductase

Tao Li, Chun-Yun Chang, Da-Yun Jin +3

Nature

Human Requirement for N-3 Polyunsaturated Fatty Acids

Artemis P. Simopoulos

Poultry Science

The diet of our ancestors was less dense in calories, being higher in fiber, rich in fruits, vegetables, lean meat, and fish. As a result, the diet was lower in total fat and saturated fat, but...

Robustness of partial least-squares method for estimating latent variable quality structures

Claes M. Cassel, Peter Hackl, Anders Westlund

Journal of Applied Statistics

Latent variable structural models and the partial least-squares (PLS) estimation procedure have found increased interest since being used in the context of customer satisfaction measurement. The...

Venous Thromboembolism Prophylaxis and Treatment in Patients With Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update

Gary H. Lyman, Alok A. Khorana, Nicole M. Kuderer +15

Journal of Clinical Oncology

Most hospitalized patients with cancer require thromboprophylaxis throughout hospitalization. Thromboprophylaxis is not routinely recommended for outpatients with cancer. It may be considered for...

Betalains: properties, sources, applications, and stability – a review

Henriette Monteiro Cordeiro de Azeredo

International Journal of Food Science & Technology

Summary Consumers are increasingly avoiding foods containing synthetic colourants, which lead food industries to replace them by natural pigments, such as carotenoids, betalains, anthocyanins and...

Quality and safety standards in the food industry, developments and challenges

Jacques Trienekens, P.J.P. Zuurbier

International Journal of Production Economics

Health properties of resistant starch

Anne P. Nugent

Nutrition Bulletin

Summary Resistant starch (RS) refers to the portion of starch and starch products that resist digestion as they pass through the gastrointestinal tract. RS is an extremely broad and diverse range of...

Magnesium: physiology and pharmacology

William Fawcett, Elizabeth Haxby, D. A. Male

British Journal of Anaesthesia

Casein Interactions: Casting Light on the Black Boxes, the Structure in Dairy Products

David S. Horne

International Dairy Journal

Subcutaneous Low-Molecular-Weight Heparin Compared with Continuous Intravenous Heparin in the Treatment of Proximal-Vein Thrombosis

Russell D. Hull, Gary E. Raskob, Graham F. Pineo +15

New England Journal of Medicine

Low-molecular-weight heparin is at least as effective and as safe as classic intravenous heparin therapy under the conditions of this study and more convenient to administer. The simplified therapy...

A review of child stunting determinants in <scp>Indonesia</scp>

Ty Beal, Alison Tumilowicz, Aang Sutrisna +2

Maternal and Child Nutrition

Child stunting reduction is the first of 6 goals in the Global Nutrition Targets for 2025 and a key indicator in the second Sustainable Development Goal of Zero Hunger. The prevalence of child...

Point of Use Household Drinking Water Filtration: A Practical, Effective Solution for Providing Sustained Access to Safe Drinking Water in the Developing World

Mark D. Sobsey, Christine E. Stauber, Lisa M. Casanova +2

Environmental Science & Technology

The lack of safe water creates a tremendous burden of diarrheal disease and other debilitating, life-threatening illnesses for people in the developing world. Point-of-use (POU) water treatment...

Bacteriocins from Lactic Acid Bacteria: Production, Purification, and Food Applications

Luc De Vuyst, Frédéric Leroy

Microbial Physiology

In fermented foods, lactic acid bacteria (LAB) display numerous antimicrobial activities. This is mainly due to the production of organic acids, but also of other compounds, such as bacteriocins and...

The growth inhibitory factor that is deficient in the Alzheimer's disease brain is a 68 amino acid metallothionein-like protein

Yoko Uchida, Koji Takio, Koiti Titani +2

Neuron

Interactions of commensal and pathogenic microorganisms with the intestinal mucosal barrier

Eric C. Martens, Mareike Neumann, Mahesh S. Desai

Nature Reviews Microbiology

Some Current Insights into Oxidative Stress

Zdeňka Ďuračková

Physiological Research

Oxidative stress is a phenomenon associated with pathogenetic mechanisms of several diseases including atherosclerosis, neurodegenerative diseases, such as Alzheimer's and Parkinson's disease,...

Mechanisms of probiotic actions – A review

Tobias A. Oelschlaeger

International Journal of Medical Microbiology

Comparison of the World Health Organization (WHO) Child Growth Standards and the National Center for Health Statistics/WHO international growth reference: implications for child health programmes

Mercedes de Onís, Adelheid W. Onyango, Elaine Borghi +2

Public Health Nutrition

The WHO standards provide a better tool to monitor the rapid and changing rate of growth in early infancy. Their adoption will have important implications for child health with respect to the...

Links Between Dietary Salt Intake, Renal Salt Handling, Blood Pressure, and Cardiovascular Diseases

Pierre Meneton, Xavier Jeunemaı̂tre, H. E. de Wardener +1

Physiological Reviews

Epidemiological, migration, intervention, and genetic studies in humans and animals provide very strong evidence of a causal link between high salt intake and high blood pressure. The mechanisms by...

Users' Guides to the Medical Literature

Gordon Guyatt

JAMA

<h3>CLINICAL SCENARIO</h3> You are a general internist who is asked to see a 65-year-old man with controlled hypertension and a 6-month history of atrial fibrillation resistant to cardioversion....

Antimicrobial activity of eugenol and essential oils containing eugenol: A mechanistic viewpoint

Anna Marchese, Ramona Barbieri, Erika Coppo +9

Critical Reviews in Microbiology

Eugenol is a hydroxyphenyl propene, naturally occurring in the essential oils of several plants belonging to the Lamiaceae, Lauraceae, Myrtaceae, and Myristicaceae families. It is one of the major...

Multilocus Sequence Typing as a Replacement for Serotyping in Salmonella enterica

Mark Achtman, John Wain, François‐Xavier Weill +11

PLoS Pathogens

Salmonella enterica subspecies enterica is traditionally subdivided into serovars by serological and nutritional characteristics. We used Multilocus Sequence Typing (MLST) to assign 4,257 isolates...

Bifidobacterium spp. and Lactobacillus acidophilus: biological, biochemical, technological and therapeutical properties relevant for use as probiotics

Ana Gomes, F. Xavier Malcata

Trends in Food Science & Technology

Enzymatic Defenses of the Mouse Heart Against Reactive Oxygen Metabolites

James H. Doroshow, Gershon Y. Locker, Charles E. Myers

Journal of Clinical Investigation

The endogenous defenses of the mouse heart against reactive oxygen metabolites were investigated. The activities of three enzymes capable of detoxifying activated oxygen were determined in both the...

Learning Mechanisms in Food Selection

Charles L. Kutscher

Neuroscience & Biobehavioral Reviews

Plasmid-controlled colonization factor associated with virulence in Esherichia coli enterotoxigenic for humans

D. Gareth Evans, Richard P. Silver, David J. Evans +2

Infection and Immunity

An enterotoxin-producing strain of Escherichia coli isolated from a case of cholera-like diarrhea (E. coli strain H-10407) was found to possess a surface-associated colonization factor. Colonization...

Chemical Composition of Selected Edible Nut Seeds

Mahesh Venkatachalam, Shridhar K. Sathe

Journal of Agricultural and Food Chemistry

Commercially important edible nut seeds were analyzed for chemical composition and moisture sorption. Moisture (1.47-9.51%), protein (7.50-21.56%), lipid (42.88-66.71%), ash (1.16-3.28%), total...

Threats to Water Supplies in the Tropical Andes

Raymond S. Bradley, Mathias Vuille, Henry F. Díaz +1

Science

Climate models predict that greenhouse warming will cause temperatures to rise faster at higher than at lower altitudes. In the tropical Andes, glaciers may soon disappear, with potentially grave...

Fatty acid composition, including conjugated linoleic acid, of intramuscular fat from steers offered grazed grass, grass silage, or concentrate-based diets.

P. French, Catherine Stanton, Fergal Lawless +4

Journal of Animal Science

The effects of grazed grass, grass silage, or concentrates on fatty acid composition and conjugated linoleic acid (cis-9, trans-11-18:2; CLA) concentrations of i.m. fat of steers fed to achieve...

Protein–polysaccharide interactions

J.L. Doublier, Catherine Garnier, D. Renard +1

Current Opinion in Colloid & Interface Science

Probiotic Spectra of Lactic Acid Bacteria (LAB)

A. Satyanarayan Naidu, Wayne R. Bidlack, Roger Clemens

Critical Reviews in Food Science and Nutrition

Lactic acid bacteria (LAB) and their probio-active cellular substances exert many beneficial effects in the gastrointestinal tract. LAB prevent adherence, establishment, and replication of several...

Revision of Campylobacter, Helicobacter, and Wolinella Taxonomy: Emendation of Generic Descriptions and Proposal of Arcobacter gen. nov.

Peter Vandamme, Enevold Falsen, R. Rossau +4

International Journal of Systematic Bacteriology

Hybridization experiments were carried out between DNAs from more than 70 strains of Campylobacter spp. and related taxa and either 3H-labeled 23S rRNAs from reference strains belonging to...

Developmental disabilities among children younger than 5 years in 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

Bolajoko O. Olusanya, Adrian Davis, Donald Wertlieb +27

The Lancet Global Health

The Bill & Melinda Gates Foundation.

Structural and functional characterization of kidney bean and field pea protein isolates: A comparative study

Khetan Shevkani, Narpinder Singh, Amritpal Kaur +1

Food Hydrocolloids

Lag Phase Is a Distinct Growth Phase That Prepares Bacteria for Exponential Growth and Involves Transient Metal Accumulation

Matthew D. Rolfe, Christopher J. Rice, Sacha Lucchini +9

Journal of Bacteriology

Lag phase represents the earliest and most poorly understood stage of the bacterial growth cycle. We developed a reproducible experimental system and conducted functional genomic and physiological...

Copper Metallochaperones

Nigel J. Robinson, Dennis R. Winge

Annual Review of Biochemistry

The current state of knowledge on how copper metallochaperones support the maturation of cuproproteins is reviewed. Copper is needed within mitochondria to supply the Cu(A) and intramembrane Cu(B)...

Surfactants Used in Food Industry: A Review

Iva Kralova, Johan Sjöblom

Journal of Dispersion Science and Technology

The understanding of the formation, structures, and properties of emulsions is essential to the creation and stabilization of structures in food. The increasing use of surfactants, the identification...

The roles of long-chain polyunsaturated fatty acids in pregnancy, lactation and infancy: review of current knowledge and consensus recommendations

Berthold Koletzko, Eric L. Lien, Carlo Agostoni +16

Journal of Perinatal Medicine

This paper reviews current knowledge on the role of the long-chain polyunsaturated fatty acids (LC-PUFA), docosahexaenoic acid (DHA, C22:6n-3) and arachidonic acid (AA, 20:4n-6), in maternal and term...

<b>zt</b>: A Software Tool for Simple and Partial Mantel Tests

Éric Bonnet, Yves Van de Peer

Journal of Statistical Software

Different methods of data analysis (e.g. clustering and ordination) are based on distance matrices. In some cases, researchers may wish to compare several distance matrices with one another in order...

Quinolone and Macrolide Resistance in Campylobacter jejuni and C. coli: Resistance Mechanisms and Trends in Human Isolates

Jørgen Engberg, Frank M. Aarestrup, Diane E. Taylor +2

Emerging infectious diseases

The incidence of human Campylobacter jejuni and C. coli infections has increased markedly in many parts of the world in the last decade as has the number of quinolone-resistant and, to a lesser...

Immune Dysfunction as a Cause and Consequence of Malnutrition

Claire D. Bourke, James A. Berkley, Andrew J. Prendergast

Trends in Immunology

Malnutrition, which encompasses under- and overnutrition, is responsible for an enormous morbidity and mortality burden globally. Malnutrition results from disordered nutrient assimilation but is...

The microbial ecology of wine grape berries

André Barata, Manuel Malfeito‐Ferreira, V. Loureiro

International Journal of Food Microbiology

The Molecular Basis of Individual Differences in Phenylthiocarbamide and Propylthiouracil Bitterness Perception

Bernd Bufe, Paul Breslin, Christina Kühn +6

Current Biology

Prevention of Venous Thromboembolism in General Surgical Patients

G. Patrick Clagett, Joan Reisch

Annals of Surgery

The results of randomized clinical trials evaluating commonly used methods of deep vein thrombosis (DVT) prophylaxis in moderate- and high-risk general surgery patients were pooled to obtain an...

Supplemental ascorbate in the supportive treatment of cancer: Prolongation of survival times in terminal human cancer.

Ewan Cameron, Linus Pauling

Proceedings of the National Academy of Sciences

Ascorbic acid metabolism is associated with a number of mechanisms known to be involved in host resistance to malignant disease. Cancer patients are significantly depleted of ascorbic acid, and in...

Rivaroxaban for Thromboprophylaxis in High-Risk Ambulatory Patients with Cancer

Alok A. Khorana, Gerald A. Soff, Ajay K. Kakkar +19

New England Journal of Medicine

In high-risk ambulatory patients with cancer, treatment with rivaroxaban did not result in a significantly lower incidence of venous thromboembolism or death due to venous thromboembolism in the...

Intestinal microflora in early infancy: composition and development

Silvia Fanaro, R Chierici, Pietro Guerrini +1

Acta Paediatrica

The neonatal intestinal microbiota is a complex ecosystem composed of numerous genera, species and strains of bacteria. This enormous cell mass performs a variety of unique activities that affect...

Incidence of Venous Thromboembolism: A Community-based Study in Western France

Emmanuel Oger, the EPI-GETBO Study Group

Thrombosis and Haemostasis

Summary The incidence of venous thromboembolism has been studied during one year in a defined population of 342,000 inhabitants. The overall incidence (95% confidence interval) of venous...